I was reading through an article on the side effects of caffeine (one of the things I'm having a hard time giving up completely is my diet coke--I'm still drinking about a can or bottle a day), and it doesn't look like small dosages bother most people, but apparently if you consume a lot of caffeine (i.e. 1000 mg or about ten 6-oz cups of coffee a day), then it could cause heartburn.
Other side effects at that dosage can be problems with conception and bowel irregularity. Even people who drink less aren't off the hook for side effects. Those who consume 250 mg a day, may experience insomnia, restlessness, irritability, nervousness, headaches, hand tremors, extra heartbeats and an inability to concentrate.
Though I don't think many of us are willing to give up our caffeine beverage of choice (whether it's diet coke with lime, or the more popular coffee drinks), it's definitely a good idea to limit intake if possible...
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